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- $Unique_ID{BRK00464}
- $Pretitle{}
- $Title{What is "Sweet Syndrome"?}
- $Subject{Sweet's syndrome rash pain Ill Defined Symptoms symptom skin
- eruptions lesions pustules acute febrile neutrophilic dermatosis white cells
- neutrophils leukemia prednisone}
- $Volume{N-20}
- $Log{}
-
- Copyright (c) 1991-92,1993 Tribune Media Services, Inc.
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-
- What is "Sweet Syndrome"?
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- QUESTION: My friend's daughter has been diagnosed as having "Sweet Syndrome".
- She can tell my friend nothing about the disease except that she is on
- prednisone. What can you tell us about this? Apparently it is not common.
- You cannot imagine how important this is to us.
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- ANSWER: Described first by Dr. R.D. Sweet in 1964, Sweet's Syndrome is a skin
- disease that occurs in women of middle age. An infection usually occurs
- before the onset of this condition, which consists of painful eruptions on the
- skin of the limbs, face and neck. As the rash progresses the lesions turn
- into pustules, and the course of the illness is marked by a high, persistent
- temperature. The condition is also known as "acute febrile neutrophilic
- dermatosis," because a microscopic examination of tissue from the skin plaques
- reveals many white cells (neutrophils) within the cell structure of the skin.
- The white cell count in the blood is also elevated somewhat, and at least one
- published paper links Sweet's Syndrome to acute leukemia. Research into the
- cause of the condition has revealed little, and the current opinion is that
- the condition may result from the patient's hypersensitivity to the bug that
- caused the original infection. Although antibiotics are apparently
- ineffective in treating the syndrome, steroids (prednisone) can be most useful
- in controlling the condition, and are effective for as long as they are given.
- The illness may last for two weeks or more, and relapses are common, usually
- preceded by infections. A call from a concerned parent to the physician
- should result in more information about this patient's condition.
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-
- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
-